This study evaluates the outcome of myeloablative chemo-radiotherapy and autologous stem cell transplantation (ASCT) in children with Hodgkin's disease (HD). Twenty children aged 5 to 18 years (median 10.8 years) at diagnosis, with relapsed, refractory or very poor prognosis HD, underwent ASCT in eight hospitals of our country. Status at transplant was: second complete remission (CR2): n = 12; further CR (CR >2): n = 3, partial remission (PR): n = 2, relapse: n = 2 and first CR (CR1): n = 1. Eighteen patients received chemotherapy-based conditioning regimens: cyclophosphamide, carmustine and etoposide (CBV): 11 (55

作者：A, Verdeguer；N, Pardo；L, Madero；A, Martinez；E, Bureo；J M, Fernández；A, Mu?oz；T, Olivé；R, Fernández-Delgado；J, Cubells；M A, Diaz；A, Sastre

来源：Bone marrow transplantation 2000 年 25卷 1期