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We report on a child with a metastasising medulloblastoma which was assessed by MR diffusion imaging and 1H MR spectroscopy (MRS). Reduced mean apparent diffusion coefficients and a high amount of taurine could be demonstrated. This is the first reported case of high taurine in medulloblastoma in vivo and confirms earlier in vitro findings. It is suggested that the changes on diffusion imaging, possibly reflecting the small-cell histology of the tumour and high taurine in MRS, are indicative of medulloblastoma.

作者:M, Wilke;A, Eidenschink;S, Müller-Weihrich;D P, Auer

来源:Acta radiologica (Stockholm, Sweden : 1987) 2001 年 42卷 1期

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作者:
M, Wilke;A, Eidenschink;S, Müller-Weihrich;D P, Auer
来源:
Acta radiologica (Stockholm, Sweden : 1987) 2001 年 42卷 1期
We report on a child with a metastasising medulloblastoma which was assessed by MR diffusion imaging and 1H MR spectroscopy (MRS). Reduced mean apparent diffusion coefficients and a high amount of taurine could be demonstrated. This is the first reported case of high taurine in medulloblastoma in vivo and confirms earlier in vitro findings. It is suggested that the changes on diffusion imaging, possibly reflecting the small-cell histology of the tumour and high taurine in MRS, are indicative of medulloblastoma.