Multiple studies have suggested an association between Chlamydia pneumoniae infection and atherosclerotic vascular disease. We investigated whether serological markers of C. pneumoniae infection were associated with acute stroke or transient ischaemic attack (TIA), exclusively in elderly patients.One-hundred white patients aged over 65 years admitted with acute stroke or TIA, and 87 control patients admitted with acute non-cardiopulmonary, non-infective disorders were recruited prospectively. Using an enzyme-linked immunosorbent assay kit, the presence of C. pneumoniae immunoglobulins IgA, IgG, IgM in patients' sera was determined.The seroprevalence of C. pneumoniae-specific IgA, IgG, IgM were 63, 71, and 14

作者：Joseph, Ngeh；Sandeep, Gupta；Colin, Goodbourn；Barnabas, Panayiotou；Geraldine, McElligott

来源：Cerebrovascular diseases (Basel, Switzerland) 2003 年 15卷 1-2期