Rhabdomyosarcomas (RMS) are soft tissue sarcomas resembling developing skeletal muscle, and pleomorphic rhabdomyosarcomas (PRMS) are a rare nonpediatric entity. Little molecular cytogenetic information exists for PRMS, and their relationship to other subtypes of rhabdomyosarcoma and other sarcomas is unclear. Chromosomal imbalances were determined in seven well-characterized cases of PRMS using comparative genomic hybridization. The smallest overlapping regions of gain were 1p22 approximately p33 (71
作者:Anthony, Gordon;Aidan, McManus;John, Anderson;Cyril, Fisher;Syuiti, Abe;Takayuki, Nojima;Kathy, Pritchard-Jones;Janet, Shipley
来源:Cancer genetics and cytogenetics 2003 年 140卷 1期