To describe the incidence and characteristics of serum sickness (SS) following administration of Wyeth Antivenin (Crotalidae) Polyvalent (ACP).A retrospective chart review was conducted involving presumed rattlesnake bite victims referred to our poison center. Serum sickness was defined as unexplained rash developing 3 to 21 days following the administration of ACP. Patients were monitored until complete resolution of all symptoms. Data collected included total number of ACP vials administered, associated signs and symptoms, duration of signs and symptoms, and medications used to treat SS.Of the 181 cases included in our study, SS occurred in 102 (56

作者：Frank, LoVecchio；Jane, Klemens；Elizabeth BoAnn, Roundy；Annie, Klemens

来源：Wilderness & environmental medicine 2003 年 14卷 4期