A TNF region haplotype offers protection from typhoid fever in Vietnamese patients.-临床诊疗知识库

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The genomic region surrounding the TNF locus on human chromosome 6 has previously been associated with typhoid fever in Vietnam (Dunstan et al. in J Infect Dis 183:261-268, 2001). We used a haplotypic approach to understand this association further. Eighty single nucleotide polymorphisms (SNPs) spanning a 150 kb region were genotyped in 95 Vietnamese individuals (typhoid case/mother/father trios). A subset of data from 33 SNPs with a minor allele frequency of >4.3

作者：Sarah J, Dunstan；Thi Hue, Nguyen；Kirk, Rockett；Julian, Forton；Andrew P, Morris；Mahamadou, Diakite；Ngoc Lanh, Mai；Thi Phuong, Le；Deborah, House；Christopher M, Parry；Vinh, Ha；T Hieu, Nguyen；Gordon, Dougan；Tinh Hien, Tran；Dominic, Kwiatowski；Jeremy J, Farrar

来源：Human genetics 2007 年 122卷 1期

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A TNF region haplotype offers protection from typhoid fever in Vietnamese patients.

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作者：

Sarah J, Dunstan；Thi Hue, Nguyen；Kirk, Rockett；Julian, Forton；Andrew P, Morris；Mahamadou, Diakite；Ngoc Lanh, Mai；Thi Phuong, Le；Deborah, House；Christopher M, Parry；Vinh, Ha；T Hieu, Nguyen；Gordon, Dougan；Tinh Hien, Tran；Dominic, Kwiatowski；Jeremy J, Farrar

来源：

Human genetics 2007 年 122卷 1期

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