The objective was to determine the impact of the coexpression of epidermal growth factor receptor (EGFR) and tumor marker c-erbB-2 on disease-free survival (DFS) and pelvic relapse-free survival (PRFS) in patients with locally advanced cervical cancer (LACC) receiving concurrent chemoradiotherapy.The expression of EGFR and c-erbB-2 was assessed by immunohistochemistry, which was centralized and blinded to outcome. Univariate and multivariate analyses were used to evaluate the impact of EGFR and c-erbB-2 on DFS and PRFS.170 patients with LACC were included and received concurrent chemoradiotherapy. 25 (15
作者:José, Pérez-Regadera;Alfonso, Sánchez-Mu?oz;Javier, De-la-Cruz;Claudio, Ballestín;David, Lora;Rosa, García-Martín;Cesar, Mendiola;Lorenzo, Alonso;Emilio, Alba;Eduardo, Lanzós
来源:Oncology 2009 年 76卷 2期