The purpose of this study was to determine changes in screening and performance of invasive diagnostic procedures for Down syndrome between 2001 and 2007.The Society for Maternal-Fetal Medicine members completed a survey in 2007 regarding screening tests and diagnostic procedures for Down syndrome. With the use of descriptive statistics, the chi(2) test, and the Student t test, responses from 2007 were compared with responses from a similar 2001 survey.Performance of first-trimester screening more than doubled from 2001-2007 (43.1

作者：Yu Ming Victor, Fang；Peter, Benn；Winston, Campbell；Jay, Bolnick；Anne Marie, Prabulos；James F X, Egan

来源：American journal of obstetrics and gynecology 2009 年 201卷 1期