Some studies report differences in opioid withdrawal between racial/ethnic groups. However, it is not known if these differences are reflected in differential treatment response. Data from National Institute on Drug Abuse (NIDA) Clinical Trials Network-003 were used to examine racial/ethnic differences before and during stabilization with buprenorphine. At induction, non-Hispanic Caucasians had higher objective and subjective withdrawal scores and greater opioid craving than minority participants. No significant between-group differences were observed on these scales following buprenorphine. Non-Hispanic Caucasians and Hispanics reported more adverse events than African Americans. Although ethnic and racial differences were observed prior to buprenorphine treatment, scores following buprenorphine treatment were similar between groups.

作者：E Sherwood, Brown；Carlos, Tirado；Abu, Minhajuddin；Maureen, Hillhouse；Bryon, Adinoff；Walter, Ling；Geetha, Doraimani；Christie, Thomas

来源：Journal of ethnicity in substance abuse 2010 年 9卷 2期