There is a paucity of information on risk factors of prostate cancer, especially those related to dietary and lifestyle among Asian populations.This study aimed to determine the relationship between dietary intake (macronutrients, fruits, vegetables and lycopene), lifetime physical activity and oxidative DNA damage with prostate cancer.A case control study was carried out among 105 subjects (case n=35, control n=70), matched for age and ethnicity. Data on sociodemographic, medical, dietary intake, consumption of lycopene rich food and lifetime physical activity were obtained through an interview based questionnaire. Anthropometric measurements including weight, height and waist hip circumferences were also carried out on subjects. A total of 3 mL fasting venous blood was drawn to assess lymphocyte oxidative DNA damage using the alkaline comet assay.Cases had a significantly higher intake of fat (27.7 ± 5.5
作者:Suzana, Shahar;Siti, Shafurah;Nur Suraiya Abu, Hasan Shaari;Roslee, Rajikan;Nor Fadilah, Rajab;Babak, Golkhalkhali;Zulkifli Md, Zainuddin
来源:Asian Pacific journal of cancer prevention : APJCP 2011 年 12卷 3期