To assess the validity of Diabetes in Pregnancy Study Group India (DIPSI) guidelines, a modified version of the WHO criterion to diagnose gestational diabetes mellitus (GDM).A total of 1 463 consecutive pregnant women in the second and third trimester of pregnancy underwent 75 g oral glucose tolerance test (OGTT) and 2-h plasma glucose (PG) was measured by the glucose oxidase-peroxidase (GOD-POD) method. GDM was diagnosed with 2-h PG ≥ 7.8 mmol/L (WHO criteria) and the rest were classified as normal glucose tolerant (NGT) women. GDM women were advised medical nutrition therapy (MNT) for two weeks. Those who failed to reach the target glycemic level of FPG < 5.0 mmol/L and 2-h PG < 6.67 mmol/L with MNT were advised insulin. All of them were followed throughout pregnancy until delivery. Birth weight of 90th percentile (> 3.45 kg) in the neonates was considered as macrosomia (primary outcome).The mean maternal age and body mass index were 23.60±3.32 years and 21.5±4.06 kg/m(2) respectively. The mean gestational age was 27.9±5.56 weeks. DIPSI criterion identified 196 women (13.4
作者:V, Balaji;Madhuri, Balaji;C, Anjalakshi;A, Cynthia;T, Arthi;V, Seshiah
来源:Indian journal of endocrinology and metabolism 2011 年 15卷 3期