To study the role of capsaicin-sensitive afferent nerves in Helicobacter pylori (H. pylori) positive chronic gastritis before and after eradication.Gastric biopsy samples were obtained from corpus and antrum mucosa of 20 healthy human subjects and 18 patients with H. pylori positive chronic gastritis (n = 18) before and after eradication. Traditional gastric mucosal histology (and Warthin-Starry silver impregnation) and special histochemical examinations were carried out. Immunohistochemistry for capsaicin receptor (TRVP1), calcitonin gene-related peptide (CGRP) and substance P (SP) were carried out by the labeled polymer immunohistological method (Lab Vision Co., USA) using polyclonal rabbit and rat monoclonal antibodies (Abcam Ltd., UK).Eradication treatment was successful in 16 patients (89

作者：Lilla, Lakner；András, D?m?t?r；Csaba, Tóth；Imre L, Szabó；Agnes, Meczker；Rebeka, Hajós；László, Kereskai；Gy?rgy, Szekeres；Zoltán, D?br?nte；Gyula, Mózsik

来源：World journal of gastrointestinal pharmacology and therapeutics 2011 年 2卷 5期