Aim of the study was to analyze temporal trends in prevalence of hyponatremia over four decades in different settings. A systematic review of the literature from 1966 to 2009 yielded prevalences of hyponatremia, with standard errors (SE) and pooled estimated means (PEM), calculated by year and setting (geriatric, ICU, other hospital wards, psychiatric hospitals, nursing homes, outpatients). 53 studies were included. Prevalence of hyponatremia was stable from 1976 to 2006, and higher on geriatric wards accept for ICU: e.g. PEM prevalence of mild hyponatremia (serum sodium <135 mM) was 22.2

作者：Cyndie K, Mannesse；Ari?l M, Vondeling；Rob J, van Marum；Wouter W, van Solinge；Toine C G, Egberts；Paul A F, Jansen

来源：Ageing research reviews 2013 年 12卷 1期