High aortic augmentation index predicts mortality and cardiovascular events in men from a general population, but not in women.-临床诊疗知识库

High aortic augmentation index predicts mortality and cardiovascular events in men from a general population, but not in women.

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作者：

Julie Hjorts?, Janner；Nina Skavlan, Godtfredsen；Steen, Ladelund；J?rgen, Vestbo；Eva, Prescott

来源：

European journal of preventive cardiology 2013 年 20卷 6期

标签：

AIx arterial stiffness augmentation index cardiovascular events mortality

A recent meta-analysis concluded that augmentation index (AIx), a measure of pulse wave reflections influencing the central blood pressure, is related to mortality and cardiovascular disease (CVD) events and is likely to be clinically useful. However, prospective data based on non high-risk populations and women are lacking.In a random sample comprising 1300 men and 1773 women from Copenhagen, Denmark, AIx was measured non-invasively by use of the SphygmoCor device. The population was followed prospectively for a mean of 6.5 years for all-cause mortality and a combined CVD end point (time to first myocardial infarction, ischaemic cerebrovascular disease, percutaneous coronary intervention, coronary by-pass graft, or death from any cause). In men, hazard ratio (HR) in highest AIx tertile vs. lowest was 1.68 (95

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