In this study, we investigated p53 and p16 deletions, and chromosome 9 and 17 amplifications in pancreatic ductal adenocarcinoma (PDAC), and further analyzed their associations with clinical characteristics and prognosis of PDAC. A total of 32 PDAC and 23 peritumoral tissues were collected. Molecular abnormalities of CEP9/p16 and CEP17/p53 were detected using Fluorescence in situ hybridization (FISH). Deletions of p16 and p53 were detected in 50
作者:Yanli, Luo;Ling, Tian;Ye, Feng;Miaoying, Yi;Xiafang, Chen;Qian, Huang
来源:Pathology oncology research : POR 2013 年 19卷 1期