Pregnancy and arterial hypertension (AH) have a prohypertrophic effect on the heart. It is suspected that the 2 conditions combined cause disproportionate myocardial hypertrophy. We sought to evaluate myocardial hypertrophy (LVH) and left ventricular function in normotensive and hypertensive women in the presence or absence of pregnancy.This prospective cross-sectional study included 193 women divided into 4 groups: hypertensive pregnant (HTP; n = 57), normotensive pregnant (NTP; n = 47), hypertensive nonpregnant (HTNP; n = 41), and normotensive nonpregnant (NTNP; n = 48). After clinical and echocardiographic evaluation, the variables were analyzed using 2-way analysis of variance with pregnancy and hypertension as factors. Left ventricular mass (LVM) was compared using nonparametric analysis of variance and Dunn's test. Predictors of LVH and diastolic dysfunction were analyzed using logistic regression (significance level, P < 0.05).Myocardial hypertrophy was independently associated with hypertension (odds ratio (OR) = 11.1, 95
作者:Silméia Garcia, Zanati Bazan;Veratherezinha Medeiros, Borges;Luís Cuadrado, Martin;Claudia Garcia, Magalh?es;Jo?o Carlos, Hueb;Liciana Vaz, de Arruda Silveira;José Carlos, Pera?oli;Beatriz Bojikian, Matsubara
来源:American journal of hypertension 2013 年 26卷 6期