Lack of recognition of early symptoms of acute posterior circulation ischaemic stroke might delay timely diagnosis and treatment with tissue plasminogen activator.We hypothesized that patients with posterior circulation stroke receive delayed thrombolytic treatment in comparison to anterior circulation stroke. We investigated the differences in times to evaluation or treatment between patients with anterior circulation ischaemic stroke and posterior circulation stroke in our aim to understand the barriers that might have caused these delays.A cross-sectional study was conducted using consecutive patients presenting to our tertiary academic centre with acute ischaemic stroke who were treated with intravenous tissue plasminogen activator within 4·5 h from symptom onset. We compared demographics, stroke severity, symptoms and signs, and time intervals among onset, emergency department arrival, emergency department physician evaluation, neurologist evaluation, brain imaging, and tissue plasminogen activator treatment in patients with anterior circulation stroke and posterior circulation stroke.Among 252 patients treated with intravenous tissue plasminogen activator, 12

作者：Amrou, Sarraj；Sarah, Medrek；Karen, Albright；Sheryl, Martin-Schild；Wafi, Bibars；Farhaan, Vahidy；James C, Grotta；Sean I, Savitz

来源：International journal of stroke : official journal of the International Stroke Society 2015 年 10卷 5期