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Studies over 5 decades have examined ABO blood groups and risk of pancreatic cancer in Western, Asian, and other populations, though no systematic review has been published. We studied data from 908 pancreatic cancer cases and 1,067 population controls collected during December 2006-January 2011 in urban Shanghai, China, and reviewed the literature for all studies of this association. Random-effects meta-analysis provided summary odds ratio estimates according to blood group and by populations endemic versus nonendemic for cytotoxin-associated gene A (CagA)-positive Helicobacter pylori. In our Shanghai study, versus group O, only ABO group A was associated with risk (odds ratio (OR) = 1.60, 95

作者:Harvey A, Risch;Lingeng, Lu;Jing, Wang;Wei, Zhang;Quanxing, Ni;Yu-Tang, Gao;Herbert, Yu

来源:American journal of epidemiology 2013 年 177卷 12期

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作者:
Harvey A, Risch;Lingeng, Lu;Jing, Wang;Wei, Zhang;Quanxing, Ni;Yu-Tang, Gao;Herbert, Yu
来源:
American journal of epidemiology 2013 年 177卷 12期
标签:
ABO blood group system Asia case-control studies meta-analysis pancreatic neoplasms
Studies over 5 decades have examined ABO blood groups and risk of pancreatic cancer in Western, Asian, and other populations, though no systematic review has been published. We studied data from 908 pancreatic cancer cases and 1,067 population controls collected during December 2006-January 2011 in urban Shanghai, China, and reviewed the literature for all studies of this association. Random-effects meta-analysis provided summary odds ratio estimates according to blood group and by populations endemic versus nonendemic for cytotoxin-associated gene A (CagA)-positive Helicobacter pylori. In our Shanghai study, versus group O, only ABO group A was associated with risk (odds ratio (OR) = 1.60, 95