Development of micellar reactive oxygen species assay for photosafety evaluation of poorly water-soluble chemicals.-临床诊疗知识库

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A reactive oxygen species (ROS) assay was previously developed for photosafety assessment; however, the phototoxic potential of some chemicals cannot be evaluated because of their limited aqueous solubility. The present study was undertaken to develop a new micellar ROS (mROS) assay system for poorly water-soluble chemicals using a micellar solution of 0.5

作者：Yoshiki, Seto；Masashi, Kato；Shizuo, Yamada；Satomi, Onoue

来源：Toxicology in vitro : an international journal published in association with BIBRA 2013 年 27卷 6期

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Development of micellar reactive oxygen species assay for photosafety evaluation of poorly water-soluble chemicals.

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作者：

Yoshiki, Seto；Masashi, Kato；Shizuo, Yamada；Satomi, Onoue

来源：

Toxicology in vitro : an international journal published in association with BIBRA 2013 年 27卷 6期

标签：

CV DMSO Micellar solution NBT NaPB OECD PABA Photoreactivity Photosafety assessment Phototoxicity Poorly water-soluble chemicals ROS Reactive oxygen species SD SDS UV coefficient of variation dimethyl sulfoxide mROS assay micellar reactive oxygen species assay nitroblue tetrazolium p-aminobenzoic acid reactive oxygen species sodium dodecyl sulfate sodium phosphate buffer standard deviation the Organisation for Economic Co-operation and Development ultraviolet

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