Congestive heart failure (CHF) is associated with increased stress and alterations in metabolism, favoring catabolism over anabolism. Hormonal profiles of patients with heart failure have been assessed using serum and saliva as matrices, which are only point measurements and do not provide long-term information. Scalp hair is a novel matrix that allows for measurement of hormones over a period of several months.We aimed to evaluate whether levels of cortisol and testosterone and their ratio (C/T) in hair correlate with severity of heart failure. We conducted a prospective study in ambulatory male patients with a left ventricular ejection fraction (LVEF)≤40

作者：David, Pereg；Justin, Chan；Evan, Russell；Tatiana, Berlin；Morris, Mosseri；Jamie A, Seabrook；Gideon, Koren；Stan, Van Uum

来源：Psychoneuroendocrinology 2013 年 38卷 12期