Comparative proteomics has recently identified afamin, the newest member of the albumin gene family, as a potential biomarker for ovarian cancer. The aim of this study was the analytical and clinical evaluation of a sandwich enzyme-linked immunosorbent assay for the determination of afamin in human plasma.We evaluated precision, linearity, and detection limit of the assay, analyte stability and biological variability, determined reference values and quantified afamin concentrations in various diseases.Within-run and total coefficients of variation were <10
作者:Benjamin, Dieplinger;Margot, Egger;Christian, Gabriel;Werner, Poelz;Elisabeth, Morandell;Beata, Seeber;Florian, Kronenberg;Meinhard, Haltmayer;Thomas, Mueller;Hans, Dieplinger
来源:Clinica chimica acta; international journal of clinical chemistry 2013 年 425卷