The surgical maze procedure is highly effective in treating symptomatic atrial fibrillation but may have detrimental effects on left atrial (LA) contractile function and compliance.To describe a series of patients presenting with symptomatic pulmonary hypertension due in part to LA dysfunction after surgical maze procedures.This report includes 9 patients who (1) presented to Mayo Clinic (Rochester, MN) between 2008 and 2012 with unexplained dyspnea and pulmonary hypertension after the surgical maze procedure, (2) underwent comprehensive hemodynamic catheterization with transseptal measurement of LA pressure, (3) had large v waves on LA pressure waveforms, and (4) did not have significant mitral valve regurgitation or stenosis or pulmonary vein stenosis.Invasive hemodynamic assessment revealed (1) severe pulmonary hypertension (mean pulmonary pressure 47 ± 6 mm Hg), (2) severe LA hypertension (27 ± 4 mm Hg), (3) giant LA v waves (to 50 ± 8 mm Hg), (4) absence of LA or left ventricular a waves, and (5) blunted x descents (2 ± 1 mm Hg). Left ventricular end-diastolic pressure was also elevated (20 ± 5 mm Hg).Abnormalities in LA compliance and contractility may lead to giant LA v waves and symptomatic pulmonary hypertension after surgical maze procedures. This syndrome should be considered in the differential diagnosis for pulmonary hypertension and underscores the importance of comprehensive hemodynamic catheterization.
作者:Terrence D, Welch;Megan, Coylewright;Brian D, Powell;Samuel J, Asirvatham;Bernard J, Gersh;Joseph A, Dearani;Rick A, Nishimura
来源:Heart rhythm : the official journal of the Heart Rhythm Society 2013 年 10卷 12期