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Chronic hepatitis C virus (HCV) infection is relatively frequent in China. This study investigated the clinical, demographic, and viral and host genetic characteristics that may influence disease manifestations and clinical management.In this cross-sectional observational study, treatment-naïve Han ethnic adults with recently confirmed chronic HCV infection were enrolled at 28 hospitals across China. HCV genotype and host interleukin 28B (IL28B) genotypes were determined and compared with patient demographic parameters and medical status.Among the 997 HCV-positive patients analyzed, 56.8

作者:Huiying, Rao;Lai, Wei;Juan Carlos, Lopez-Talavera;Jia, Shang;Hong, Chen;Jun, Li;Qing, Xie;Zhiliang, Gao;Lei, Wang;Jia, Wei;Jianning, Jiang;Yongtao, Sun;Ruifeng, Yang;Hong, Li;Haiying, Zhang;Zuojiong, Gong;Lunli, Zhang;Longfeng, Zhao;Xiaoguang, Dou;Junqi, Niu;Hong, You;Zhi, Chen;Qin, Ning;Guozhong, Gong;Shuhuan, Wu;Wei, Ji;Qing, Mao;Hong, Tang;Shuchen, Li;Shaofeng, Wei;Jian, Sun;Jiaji, Jiang;Lungen, Lu;Jidong, Jia;Hui, Zhuang

来源:Journal of gastroenterology and hepatology 2014 年 29卷 3期

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作者:
Huiying, Rao;Lai, Wei;Juan Carlos, Lopez-Talavera;Jia, Shang;Hong, Chen;Jun, Li;Qing, Xie;Zhiliang, Gao;Lei, Wang;Jia, Wei;Jianning, Jiang;Yongtao, Sun;Ruifeng, Yang;Hong, Li;Haiying, Zhang;Zuojiong, Gong;Lunli, Zhang;Longfeng, Zhao;Xiaoguang, Dou;Junqi, Niu;Hong, You;Zhi, Chen;Qin, Ning;Guozhong, Gong;Shuhuan, Wu;Wei, Ji;Qing, Mao;Hong, Tang;Shuchen, Li;Shaofeng, Wei;Jian, Sun;Jiaji, Jiang;Lungen, Lu;Jidong, Jia;Hui, Zhuang
来源:
Journal of gastroenterology and hepatology 2014 年 29卷 3期
标签:
China HPV IL28B cirrhosis epidemiology natural history
Chronic hepatitis C virus (HCV) infection is relatively frequent in China. This study investigated the clinical, demographic, and viral and host genetic characteristics that may influence disease manifestations and clinical management.In this cross-sectional observational study, treatment-naïve Han ethnic adults with recently confirmed chronic HCV infection were enrolled at 28 hospitals across China. HCV genotype and host interleukin 28B (IL28B) genotypes were determined and compared with patient demographic parameters and medical status.Among the 997 HCV-positive patients analyzed, 56.8