Recent case-control studies observed an increased prevalence of nonalcoholic fatty liver disease (NAFLD) in patients with psoriasis, which is relevant in selecting optimal psoriasis treatment.We sought to compare the prevalence of NAFLD in people with psoriasis and those without psoriasis.This large prospective population-based cohort study (part of the Rotterdam Study) enrolled elderly participants (>55 years). NAFLD was diagnosed as fatty liver on ultrasonography in the absence of other liver diseases. Participants with psoriasis were identified using a validated algorithm. Multivariable logistic regression model was used to assess whether psoriasis was associated with NAFLD after adjusting for demographic, lifestyle characteristics, and laboratory findings.In total, 2292 participants were included (mean age 76.2 ± 6.0 years; 58.7

作者：Ella A M, van der Voort；Edith M, Koehler；Emmilia A, Dowlatshahi；Albert, Hofman；Bruno H, Stricker；Harry L A, Janssen；Jeoffrey N L, Schouten；Tamar, Nijsten

来源：Journal of the American Academy of Dermatology 2014 年 70卷 3期