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Multiple Sclerosis is an inflammatory disease of the central nervous system in which T cells experience a second phase of activation, which ultimately leads to axonal demyelination and neurological disability. The recent advances in stem cell therapies may serve as potential treatments for neurological disorders. There are broad types of stem cells such as neural, embryonic, mesenchymal and hematopoietic stem cells with unprecedented hope in treating many debilitating diseases. In this paper we will review the substantial literature regarding experimental and clinical use of these stem cells and possible mechanisms in the treatment of MS. These results may pave the road for the utilization of stem cells for the treatment of MS.

作者:Abdolreza, Ardeshiry Lajimi;Majid Farshdousti, Hagh;Najmaldin, Saki;Esmaeil, Mortaz;Masoud, Soleimani;Fakher, Rahim

来源:International journal of hematology-oncology and stem cell research 2013 年 7卷 1期

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作者:
Abdolreza, Ardeshiry Lajimi;Majid Farshdousti, Hagh;Najmaldin, Saki;Esmaeil, Mortaz;Masoud, Soleimani;Fakher, Rahim
来源:
International journal of hematology-oncology and stem cell research 2013 年 7卷 1期
标签:
Hematopoietic stem cells Human embryonic stem cells Mesenchymal stem cells Multiple sclerosis Neural stem cells Stem cells therapy
Multiple Sclerosis is an inflammatory disease of the central nervous system in which T cells experience a second phase of activation, which ultimately leads to axonal demyelination and neurological disability. The recent advances in stem cell therapies may serve as potential treatments for neurological disorders. There are broad types of stem cells such as neural, embryonic, mesenchymal and hematopoietic stem cells with unprecedented hope in treating many debilitating diseases. In this paper we will review the substantial literature regarding experimental and clinical use of these stem cells and possible mechanisms in the treatment of MS. These results may pave the road for the utilization of stem cells for the treatment of MS.