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We report a 55-year-old female who presented to the emergency department with acute onset quadriparesis. She was diagnosed to have acquired immunodeficiency syndrome 7 years ago and was on tenofovir based anti-retroviral therapy for past 10 months. As the patient also had hypophosphatemia, glucosuria and proteinuria Fanconi syndrome (FS) was suspected. She improved dramatically over next 12 h to regain normal power and also her renal functions improved over next few days. Tenofovir induced FS presenting as hypokalemic paralysis is very rare complication and is the first case reported from India.

作者:E P, Venkatesan;M B, Pranesh;G, Gnanashanmugam;J, Balasubramaniam

来源:Indian journal of nephrology 2014 年 24卷 2期

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作者:
E P, Venkatesan;M B, Pranesh;G, Gnanashanmugam;J, Balasubramaniam
来源:
Indian journal of nephrology 2014 年 24卷 2期
标签:
Anti-retroviral therapy Fanconi syndrome tenofovir
We report a 55-year-old female who presented to the emergency department with acute onset quadriparesis. She was diagnosed to have acquired immunodeficiency syndrome 7 years ago and was on tenofovir based anti-retroviral therapy for past 10 months. As the patient also had hypophosphatemia, glucosuria and proteinuria Fanconi syndrome (FS) was suspected. She improved dramatically over next 12 h to regain normal power and also her renal functions improved over next few days. Tenofovir induced FS presenting as hypokalemic paralysis is very rare complication and is the first case reported from India.