Lower total and percent of high-molecular-weight adiponectin concentration in South Asian kidney transplant recipients.-临床诊疗知识库

Lower total and percent of high-molecular-weight adiponectin concentration in South Asian kidney transplant recipients.

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作者：

G V Ramesh, Prasad；Leon, Vorobeichik；Michelle M, Nash；Michael, Huang；Lindita, Rapi；Graham, Maguire；Muhammad, Mamdani；Andrew T, Yan；Philip W, Connelly

来源：

Clinical kidney journal 2012 年 5卷 2期

标签：

cardiovascular disease ethnicity renal transplantation risk factors

Ethnicity is an important determinant of post-renal transplant outcomes. Limited data are available on cardiovascular risk differences in kidney transplant recipients (KTR) based on ethnicity.A group of 129 clinically stable age-matched KTR [43 South Asian (SA), 86 Caucasian]) were assessed for plasma total and high-molecular-weight (HMW) adiponectin, cystatin C, apolipoproteins A1 and B, C-reactive protein, uric acid, urine albumin-to-creatinine ratio, estimated glomerular filtration rate (eGFR) and transplant-specific plus traditional Framingham risk factors. SA and Caucasians were compared by t-tests, Wilcoxon rank-sum or chi-square testing. Accounting for the matched design, multivariable linear regression was performed to determine predictors of adiponectin concentrations.SA did not differ from Caucasians in background cardiac disease or cardioprotective medication use or risk factors other than smoking (26 versus 56

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