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Approximately one-third of all children with epilepsy do not achieve complete seizure improvement. This study evaluated the efficacy of Vigabatrin in children with intractable epilepsy.From November 2011 to October 2012, 73 children with refractory epilepsy (failure of seizure control with the use of two or more anticonvulsant drugs) who were referred to the Children's Medical Center and Mofid Children's Hospital were included in the study. The patients were treated with Vigabatrin in addition to their previous medication, and followed-up after three to four weeks to determine the daily frequency, severity, and duration of seizures in addition to any reported side effects.Of the 67 children, 41 (61.2

作者:Mohammad-Mahdi, Taghdiri;Mahmoud-Reza, Ashrafi;Mohammad-Kazem, Bakhshandeh-Bali;Seyedeh-Mohadeseh, Taheri-Otaghsara;Mohammad-Mahdi, Nasehi

来源:Iranian journal of pediatrics 2013 年 23卷 6期

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作者:
Mohammad-Mahdi, Taghdiri;Mahmoud-Reza, Ashrafi;Mohammad-Kazem, Bakhshandeh-Bali;Seyedeh-Mohadeseh, Taheri-Otaghsara;Mohammad-Mahdi, Nasehi
来源:
Iranian journal of pediatrics 2013 年 23卷 6期
标签:
Add-on Therapy Antiepileptic Drugs Intractable Epilepsy Vigabatrin
Approximately one-third of all children with epilepsy do not achieve complete seizure improvement. This study evaluated the efficacy of Vigabatrin in children with intractable epilepsy.From November 2011 to October 2012, 73 children with refractory epilepsy (failure of seizure control with the use of two or more anticonvulsant drugs) who were referred to the Children's Medical Center and Mofid Children's Hospital were included in the study. The patients were treated with Vigabatrin in addition to their previous medication, and followed-up after three to four weeks to determine the daily frequency, severity, and duration of seizures in addition to any reported side effects.Of the 67 children, 41 (61.2