This study is aimed at comparing the efficacy and safety of loxoprofen sodium hydrogel patch (LX-P) with loxoprofen sodium tablet (LX-T) in patients with knee osteoarthritis (OA). One hundred sixty-nine patients were enrolled in a randomized, controlled, double-blind, double-dummy, multicenter, non-inferiority trial of LX-P. Patients were randomly assigned to either LX-P or LX-T groups for a 4-week treatment. The primary efficacy endpoint was the proportion of patients with an overall improvement of ≥50

作者：Rong, Mu；Chun-de, Bao；Zhi-wei, Chen；Yi, Zheng；Guo-chun, Wang；Dong-bao, Zhao；Shao-xian, Hu；Yu-jun, Li；Zeng-wu, Shao；Zhi-yi, Zhang；Wei-guo, Xiao；Weiya, Zhang；Zhan-guo, Li

来源：Clinical rheumatology 2016 年 35卷 1期