Giant cell tumor (GCT) is primarily a bone neoplasm. Rare origin of the tumor from soft tissues has been reported. Involvement of mediastinum by GCT is even rarer. We herein describe an interesting case of huge mediastinal tumor in a young man. Radiologically, no primary osseous lesion was present throughout the body. Morphologically, tumor resembles osseous GCT with increased mitotic activity. Hence, the case was diagnosed as soft tissue GCT of low malignant potential at the rare site of mediastinum. To the best of our knowledge, the present case is the fourth reported case. Pathologists and clinicians need to be aware of the rare diagnosis of GCT in mediastinum and should carefully evaluate the clinical and radiological findings.

作者：Deepali, Jain；Sudheer, Arava；Biplab, Mishra；Sanjay, Sharma；Raju, Sharma；Rajinder, Parshad

来源：International journal of surgical pathology 2015 年 23卷 1期