Glaucoma is the second leading cause of blindness and it is related to oxidative stress based on numerous studies. Glutathione S-transferases (GSTs) are members of multigenic family, which have important role in cells as an antioxidant. In the present study, we examined the polymorphism of GSTT1 and GSTM1 deletion genotypes (T0M1, T1M0, and T0M0) in 100 Glaucoma patients (41with primary open angle glaucoma (PCAG), and 59 with primary closed angle glaucoma (POAG)) compared to 100 healthy subjects.GSTM1and GSTT1 polymorphisms were determined by multiplex polymerase chain reaction.GSTM1 and GSTT1 null deletions genotypes were determined in 22 (53.7

作者：Fatemeh Kazemi, Safa；Gholamreza, Shahsavari；Reza Zare, Abyaneh

来源：Iranian journal of basic medical sciences 2014 年 17卷 5期