Redefining diastolic dysfunction grading: combination of E/A ≤0.75 and deceleration time 140 ms and E/ε' ≥10.-临床诊疗知识库

Redefining diastolic dysfunction grading: combination of E/A ≤0.75 and deceleration time >140 ms and E/ε' ≥10.

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作者：

Hiroshi, Kuwaki；Masaaki, Takeuchi；Victor, Chien-Chia Wu；Kyoko, Otani；Yasufumi, Nagata；Atsushi, Hayashi；Mai, Iwataki；Shota, Fukuda；Hidetoshi, Yoshitani；Haruhiko, Abe；Yutaka, Otsuji

来源：

JACC. Cardiovascular imaging 2014 年 7卷 8期

标签：

diastolic dysfunction echocardiography left atrium prognosis speckle tracking

This study sought to examine left atrial (LA) mechanics and the prognostic impact of patients with echocardiographic findings of E/A ratio ≤0.75, deceleration time (DcT) of mitral E-wave >140 ms, but E/ε' ≥10.Traditional diastolic dysfunction (DD) grading system could not classify every patient into a specific group. We considered the group of patients with E/A ≤0.75, DcT >140 ms, but E/ε' ≥10 (proposed new DD grade) as a new group in the DD grading system.A total of 1,362 consecutive patients were stratified according to the new DD grading system, and the LA volumes, strain, and strain rates were measured by 2-dimensional speckle-tracking analysis. All patients were followed up to determine cardiac death and major adverse cardiac events.An E/A ≤0.75, DcT >140 ms, but E/ε' ≥10 was observed in 227 patients (17

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