Cerebral microbleeds (CMBs) are found in a substantial proportion of patients with ischemic stroke eligible for treatment with intravenous thrombolysis. Until now, there is limited data on the impact of multiple CMBs on occurrence of intracerebral hemorrhage (ICH) after intravenous thrombolysis.Between 2008 and 2013, all patients receiving MRI-based intravenous thrombolysis were identified within our prospective thrombolysis register. Number of CMBs was rated on pretreatment T2*-weighted MRI by a rater blinded to clinical data and follow-up. Outcomes of interest were occurrence of symptomatic ICH (sICH) and parenchymal hemorrhage (PH).Among 326 included patients, 52 patients had a single CMB (16.0

作者：Steffen, Dannenberg；Jan F, Scheitz；Michal, Rozanski；Hebun, Erdur；Peter, Brunecker；David J, Werring；Jochen B, Fiebach；Christian H, Nolte

来源：Stroke 2014 年 45卷 10期