Hemagglutination inhibiting (HI) antibodies correlate with influenza vaccine protection but their association with protection induced by natural infection has received less attention and was studied here.940 people from 270 unvaccinated households participated in active ILI surveillance spanning 3 influenza seasons. At least 494 provided paired blood samples spanning each season. Influenza infection was confirmed by RT-PCR on nose/throat swabs or serum HI assay conversion.Pre-season homologous HI titer was associated with a significantly reduced risk of infection for H3N2 (OR 0.61, 95

作者：Annette, Fox；Le Quynh, Mai；Le Thi, Thanh；Marcel, Wolbers；Nguyen, Le Khanh Hang；Pham Quang, Thai；Nguyen, Thi Thu Yen；Le Nguyen, Minh Hoa；Juliet E, Bryant；Tran Nhu, Duong；Dang Dinh, Thoang；Ian G, Barr；Heiman, Wertheim；Jeremy, Farrar；Nguyen Tran, Hien；Peter, Horby

来源：The Journal of infection 2015 年 70卷 2期