Maspin is known to be a tumour suppressor protein, and few studies focused upon its prognostic significance in patients with small-size lung adenocarcinoma have been reported; however, its clinical significance remains controversial. We explored the prognostic value of maspin with particular reference to its subcellular localization in patients with resected lung adenocarcinoma measuring <3 cm.Immunohistochemical analyses were performed on resected 110 specimens of lung adenocarcinoma measuring <3 cm. Maspin positivity was defined as strong expression in only the cytoplasm and was observed in 27 patients (24.5

作者：Yuzo, Takagi；Yuki, Matsuoka；Tatsushi, Shiomi；Kanae, Nosaka；Chikako, Takeda；Tomohiro, Haruki；Kunio, Araki；Yuji, Taniguchi；Hiroshige, Nakamura；Yoshihisa, Umekita

来源：Histopathology 2015 年 66卷 5期