Alternative donors, such as unrelated umbilical cord blood (UCB) and related haploidentical (haplo) donors, are more and more frequently searched for and used for patients who are candidates for allogeneic hematopoietic stem cell transplantation but are without a suitable related or unrelated donor. The aim of the current retrospective study was to compare the outcome of patients after haplo and UCB grafts prepared using a nonmyeloablative conditioning regimen.A total of 150 adult patients with high-risk hematologic diseases who underwent allogeneic hematopoietic stem cell transplantation from alternative donors at 2 centers (Paoli-Calmettes Institute [Marseille, France] and Humanitas Cancer Center [Milan, Italy]) were analyzed. Sixty-nine patients had haplo donors and 81 patients had UCB donors.The cumulative incidence of nonrecurrence mortality at 1 year was 23

作者：Jean, El-Cheikh；Roberto, Crocchiolo；Sabine, Furst；Stefania, Bramanti；Barbara, Sarina；Angela, Granata；Andrea, Vai；Claude, Lemarie；Catherine, Faucher；Bilal, Mohty；Samia, Harbi；Reda, Bouabdallah；Norbert, Vey；Armando, Santoro；Christian, Chabannon；Luca, Castagna；Didier, Blaise

来源：Cancer 2015 年 121卷 11期