The association between quantity of liver fat and the presence of metabolic syndrome needs to be assessed systematically. We aimed to determine the association between the quantity of liver fat and the presence of the metabolic syndrome in patients with biopsy-proven nonalcoholic fatty liver disease (NAFLD), independent of nonalcoholic steatohepatitis (NASH).We recruited 146 patients with well-characterized biopsy-proven NAFLD and 50 individuals without NAFLD (controls) to participate in a case-control study at the NAFLD Translational Research Unit at the University of California San Diego. Liver fat was quantified in patients with NAFLD and controls using an advanced magnetic resonance imaging-based biomarker, the proton-density-fat-fraction (MRI-PDFF). Patients with NAFLD were divided into groups based on whether they were above or below the median MRI-PDFF value (15.4

作者：Ahilan, Arulanandan；Brandon, Ang；Ricki, Bettencourt；Jonathan, Hooker；Cynthia, Behling；Grace Y, Lin；Mark A, Valasek；Joachim H, Ix；Bernd, Schnabl；Claude B, Sirlin；Rohit, Loomba

来源：Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2015 年 13卷 8期