Anderson-Fabry Disease (AFD) is an important cause of cardiomyopathy characterized by concentric left-ventricular hypertrophy (LVH). We evaluated the extent of left-atrial (LA) structural and functional remodelling in this group of patients given that LA remodelling is a marker of adverse outcomes in the presence of LVH.Clinical profiles were obtained and cardiac MRI was performed in cohorts of patients with AFD (n = 31), healthy controls (n = 23), and a positive control cohort with known concentric remodelling and LVH (CR/H, n = 21). Of patients with AFD, 58

作者：Brendan N, Putko；Haran, Yogasundaram；Kelvin, Chow；Joseph, Pagano；Aneal, Khan；D Ian, Paterson；Richard B, Thompson；Gavin Y, Oudit

来源：European heart journal cardiovascular Imaging 2015 年 16卷 10期