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[Pd(sac)(terpy)](sac)•4H2O (sac=saccharinate and terpy=2,2':6',2"-terpyridine) is newly-synthesized palladium(II) (Pd) complex. We investigated the antiproliferative and apoptotic effects of this complex on Ehrlich ascites carcinoma (EAC).EAC cells were administered to 33 Balb/c mice. Mice were divided randomly into four groups: control, cisplatin, Pd(II) complex and paclitaxel. Control group animals received 0.9

作者:Elif Ilkay, Ikitimur-Armutak;Kivilcim, Sonmez;Kadriye, Akgun-Dar;Gulbin, Sennazli;Aysegul, Kapucu;Funda, Yigit;Veysel Turan, Yilmaz;Engin, Ulukaya

来源:Anticancer research 2015 年 35卷 3期

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作者:
Elif Ilkay, Ikitimur-Armutak;Kivilcim, Sonmez;Kadriye, Akgun-Dar;Gulbin, Sennazli;Aysegul, Kapucu;Funda, Yigit;Veysel Turan, Yilmaz;Engin, Ulukaya
来源:
Anticancer research 2015 年 35卷 3期
标签:
EAC PCNA Pd(II) complex apoptosis in vivo tumor
[Pd(sac)(terpy)](sac)•4H2O (sac=saccharinate and terpy=2,2':6',2"-terpyridine) is newly-synthesized palladium(II) (Pd) complex. We investigated the antiproliferative and apoptotic effects of this complex on Ehrlich ascites carcinoma (EAC).EAC cells were administered to 33 Balb/c mice. Mice were divided randomly into four groups: control, cisplatin, Pd(II) complex and paclitaxel. Control group animals received 0.9