Long-Term Effect of Goal-Directed Weight Management in an Atrial Fibrillation Cohort: A Long-Term Follow-Up Study (LEGACY).-临床诊疗知识库

Long-Term Effect of Goal-Directed Weight Management in an Atrial Fibrillation Cohort: A Long-Term Follow-Up Study (LEGACY).

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作者：

Rajeev K, Pathak；Melissa E, Middeldorp；Megan, Meredith；Abhinav B, Mehta；Rajiv, Mahajan；Christopher X, Wong；Darragh, Twomey；Adrian D, Elliott；Jonathan M, Kalman；Walter P, Abhayaratna；Dennis H, Lau；Prashanthan, Sanders

来源：

Journal of the American College of Cardiology 2015 年 65卷 20期

标签：

ablation atrial fibrillation cardiac risk factors obesity outcomes remodeling

Obesity and atrial fibrillation (AF) frequently coexist. Weight loss reduces the burden of AF, but whether this is sustained, has a dose effect, or is influenced by weight fluctuation is unknown.This study sought to evaluate the long-term impact of weight loss and weight fluctuation on rhythm control in obese individuals with AF.Of 1,415 consecutive patients with AF, 825 had a body mass index ≥ 27 kg/m(2) and were offered weight management. After screening for exclusion criteria, 355 were included in this analysis. Weight loss was categorized as group 1 (≥ 10

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