Cerebral small vessel disease (SVD) is associated with late-onset depression and increases the risk for depression after stroke. We aimed to investigate baseline predictors of depression after long-term follow-up in patients with SVD, initially presenting with first-ever lacunar stroke, free of depression and cognitive impairment.A total of 294 patients with SVD were evaluated 3-5 years after the qualifying event. We analyzed baseline demographic data, vascular risk factors, functional status expressed as a score on modified Rankin Scale (mRS), cognitive status, presence of depression, total number of lacunar infarcts and severity of white matter hyperintensities (WMH) on MRI with Age-Related White Matter Changes scale total score (tARWMC) and Fazekas scale periventricular and deep subcortical scores.On follow-up, depression was registered in 117 (39.8

作者：Aleksandra M, Pavlovic；Tatjana, Pekmezovic；Jasna, Zidverc Trajkovic；Tamara, Svabic Medjedovic；Nikola, Veselinovic；Aleksandra, Radojicic；Milija, Mijajlovic；Gordana, Tomic；Zagorka, Jovanovic；Melanie, Norton；Nada, Sternic

来源：International journal of geriatric psychiatry 2016 年 31卷 1期