Migraine is a risk factor for clinical stroke and for subclinical white matter hyperintensities and infratentorial infarcts. These subclinical lesions are linked to small-vessel pathology. Cerebral microbleeds (CMBs) are another biomarker of small-vessel disease but have not yet been studied in migraine.Identification of CMBs in 63 migraineurs (25 with aura/35 without aura/3 unknown aura status) and 359 controls (aged, 73-85 years) from the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) magnetic resonance imaging study. We assessed the modifying role of migraine in the co-occurrence of CMBs, infarcts, and white matter hyperintensity-load.Infratentorial microbleeds were more prevalent in migraine without aura patients than controls (14

作者：Enrico B, Arkink；Gisela M, Terwindt；Anton J M, de Craen；Junya, Konishi；Jeroen, van der Grond；Mark A, van Buchem；Michel D, Ferrari；Mark C, Kruit

来源：Stroke 2015 年 46卷 7期