The heart is a major target organ for thyroid hormone action. Severe overt hypothyroidism can result in diastolic hypertension, lowered cardiac output, impaired left ventricular contractility and diastolic relaxation, pericardial effusion and bradycardia. However, the function of the atrial pacemaker is usually normal and the degree by which the heart rate slows down is often modest. Here we report the case of a 20 year old male Caucasian with severe overt hypothyroidism. He presented with syncopation due to second degree atrioventricular block type Mobitz 2 and heart failure with reduced ejection fraction (38 

作者：Apostolos, Chatzitomaris；Michael, Scheeler；Michael, Gotzmann；Roland, K?ditz；Janice, Schildroth；Kathy Miriam, Knyhala；Volkmar, Nicolas；Christoph, Heyer；Andreas, Mügge；Harald H, Klein；Johannes W, Dietrich

来源：Thyroid research 2015 年 8卷