The aim of this study was to estimate the diagnostic sensitivity of thyroid autoantibodies in individuals with a case-mix of subjects with thyroid disease representing that of the general population. We measured thyroid microsome (TMA), thyroid peroxidase (TPO), thyroglobulin (TGA) and thyroid-stimulating hormone (TSH) receptor (TRA) autoantibodies in subjects in the bottom (hyperthyroid end) and top (hypothyroid end) four percentiles of the TSH distribution from among participants in a population-based survey of individuals aged ≥40 years (the Cremona Study). TMA and TPO were the most sensitive autoantibodies in subjects in both the bottom percentiles (19.8

作者：Emanuele, Bosi；Roberto, Bianchi；Giacomo, Ruotolo；Elena, Bazzigaluppi；Cristina, Belloni；Giliola, Calori；Anna Maria, Girardi；Maria Paola, Garancini；Marina, Scavini

来源：Auto- immunity highlights 2010 年 1卷 2期