There is a dearth of prospective evidence regarding cancer of the major salivary glands. Outcomes and management of major salivary gland are based largely on retrospective series spanning many decades and changes in surgical, radiation, imaging and systemic therapy strategies and technique. We sought to report contemporary patterns of relapse and prognostic factors for major salivary gland cancer.112 patients with major salivary gland cancers underwent resection with or without adjuvant therapy between January 1997 and September 2010. Outcomes were documented with follow-up until December 2014. Survival was calculated by the Kaplan-Meier method. Log-rank test and Cox proportional hazards regression were performed with locoregional control (LRC), distant control (DC) and overall survival (OS) as the primary outcome variables.Median follow-up was 55.1 months. Rates of LRC for stage I/II and III/IV at five years were 95.7

作者：Naresh, Jegadeesh；Yuan, Liu；Roshan S, Prabhu；Kelly R, Magliocca；David M, Marcus；Kristin A, Higgins；Jeffrey M, Vainshtein；J, Trad Wadsworth；Jonathan J, Beitler

来源：Oral oncology 2015 年 51卷 8期