To investigate the association between retinal vascular tortuosity and traditional- and vascular-related risk factors in persons with diabetes.We recruited 224 diabetic patients. Retinal vascular tortuosity was measured from fundus photographs. Association of tortuosity with the following factors was assessed after adjusting for significant co-factors: diabetes duration, HbA1c, systolic blood pressure (SBP), cholesterol and body mass index (BMI), flicker-light induced retinal vasodilatation, and markers of endothelial function and inflammation (skin microvacular responses to acetylcholine iontophoresis, soluble e-selectin, inter-cellular adhesion molecule-1, vascular cell adhesion molecule-1, endothelin-1, total nitrite, C-reactive protein).Adjusting for age and gender, longer diabetes duration was associated with more tortuous retinal arterioles (mean difference in arteriolar tortuosity 5.85 × 10(-5), 95

作者：Muhammad Bayu, Sasongko；Tien Yin, Wong；Thanh T, Nguyen；Carol Y, Cheung；Jonathan E, Shaw；Ryo, Kawasaki；Ecosse L, Lamoureux；Jie Jin, Wang

来源：Current eye research 2016 年 41卷 4期