Subclinical cardiac dysfunction has been associated with increased mortality, and heart failure increases the risk of sudden cardiac death (SCD). Less well known is whether subclinical cardiac dysfunction is also a risk factor for SCD. Our objective was to assess the association between echocardiographic parameters and SCD in a community-dwelling population free of heart failure.We computed hazard ratios (HRs) for left atrium diameter, left ventricular (LV) end-diastolic dimension, LV end-systolic dimension, LV mass, qualitative LV systolic function, LV fractional shortening, and diastolic function. During a median follow-up of 6.3 years in 4,686 participants, 68 participants died because of SCD. Significant associations with SCD were observed for qualitative LV systolic function and LV fractional shortening. For moderate/poor qualitative LV systolic function, the HR for SCD was 2.54 (95

作者：Maartje N, Niemeijer；Maarten J G, Leening；Marten E, van den Berg；Albert, Hofman；Oscar H, Franco；Jaap W, Deckers；Peter R, Rijnbeek；Bruno H, Stricker；Mark, Eijgelsheim

来源：Journal of cardiac failure 2016 年 22卷 1期