Pegylated interferon-alpha plus ribavirin combination (PegIFN/RBV) therapy possesses positive effect in the secondary prevention of hepatocellular carcinoma (HCC) in chronic hepatitis C (CHC) patients. The current study aimed to assess its efficacy in the tertiary prevention and to validate the performance of the MHC class I polypeptide-related chain A (MICA) level in the prediction of hepatocellular carcinoma (HCC) recurrence.A multi-center study enrolling 105 consecutive HCC patients post curative therapies were prospectively recruited. The primary outcome measurement was recurrence of HCC.The mean observational period was 52.7 months (range = 3.9-121.5 months). Fifty-six (53.3
作者:Jee-Fu, Huang;Ming-Lun, Yeh;Ming-Lung, Yu;Chia-Yen, Dai;Chung-Feng, Huang;Ching-I, Huang;Pei-Chien, Tsai;Pei-Chen, Lin;Yao-Li, Chen;Wen-Tsan, Chang;Nai-Jen, Hou;Zu-Yau, Lin;Shinn-Cherng, Chen;Wan-Long, Chuang
来源:Journal of gastroenterology and hepatology 2015 年 30卷 12期