Adherence to, and effectiveness of, subcutaneous interferon β-1a administered by RebiSmart? in patients with relapsing multiple sclerosis: results of the 1-year, observational SMART study.-临床诊疗知识库

Adherence to, and effectiveness of, subcutaneous interferon β-1a administered by RebiSmart? in patients with relapsing multiple sclerosis: results of the 1-year, observational SMART study.

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作者：

Antonios, Bayas；Jean Christophe, Ouallet；Boris, Kallmann；Raymond, Hupperts；Ulrich, Fulda；Kurt, Marhardt

来源：

Expert opinion on drug delivery 2015 年 12卷 8期

标签：

adherence autoinjector interferon β multiple sclerosis

Patients with multiple sclerosis who have poor adherence to treatment have a higher risk of relapse than adherent patients. This study assessed adherence to, and effectiveness and convenience of, treatment with subcutaneous (sc) interferon (IFN) β-1a (Rebif®, Merck Serono SA) 44 or 22 μg three times weekly in patients with relapsing multiple sclerosis (RMS) using the RebiSmart® electronic, multidose, autoinjector for 1 year.European, multicentre, observational study among neurologists: inclusion criteria included RMS, Expanded Disability Status Scale score ≤ 6, sc IFN β-1a administered by RebiSmart for ≤ 6 weeks. The primary endpoint was cumulative adherence recorded by RebiSmart.The safety population included 912 patients, 77.4

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