Hyponatremia is the most common electrolyte disorder seen in clinical practice. Numerous studies have reported increased inhospital mortality associated to this condition, which is also an independent predictor of comorbidity in patients admitted with heart failure (HF). The objective of this study is to assess the incidence, average length of stay, associated comorbidities, readmissions and mortality caused by hyponatremia in admissions for acute heart failure from the Spanish national minimum basic data set (MBDS).Data from the Spanish national minimum basic data set (MBDS) of discharged patients who were initially diagnosed with heart failure (HF) from all internal medicine (IM) departments of Spanish National Health System (SNS) hospitals between 2005 and 2011 were analysed (ICD-9: 428; DRGs 127 and 544). A descriptive data analysis was conducted comparing the diagnosis codes and administrative variables of heart failure patients with and without hyponatremia. The chi-square test was used for qualitative variables and the Student's t test for quantitative variables. A bivariate analysis was used to detect statistical differences in the mortality of both groups, as well as mean age, Charlson index, average length of stay and readmissions. A multivariate logistic regression analysis was performed, taking intrahospital mortality and hospital readmissions as dependent variables, and age, gender, comorbidity according to the Charlson index and hyponatremia as independent variables.A total of 504,860 patients with acute heart failure were identified, of whom 11,095 (2.2

作者：Manuel, Méndez-Bailón；Raquel, Barba-Martín；Jose María, de Miguel-Yanes；Antonio, Zapatero-Gaviria；Beatriz, Calvo-Porqueras；Mariam Farid-Zahran, Osuna；Carla, Nu?ez-Fernández；Nuria, Mu?oz-Rivas；Susana, Plaza Canteli；Javier, Marco-Martínez

来源：European journal of internal medicine 2015 年 26卷 8期